Edit |   |
---|---|
Antigenic Specificity | VINC (C-term), 1012-1039 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse (predicted reactivity: chicken, porcine, rat) |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 2 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This VINC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1012-1039 amino acids from the C-terminal region of human VINC. VINC is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Defects in VCL are the cause of cardiomyopathy dilated type 1W. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. |
Immunogen | n/a |
Other Names | [Vinculin; Metavinculin; MV; VCL] |
Gene, Accession # | [VCL], Gene ID: 7414, NCBI: NP_003364.1, UniProt: P18206 |
Catalog # | MBS9206854 |
Price | $165, $370 |
Order / More Info | VINC (C-term), 1012-1039 Antibody from MYBIOSOURCE INC. |
Product Specific References | Moiseyeva E.P., Weller P.A.J. Biol. Chem. 268:4318-4325(1993) Sun N., Critchley D.R., Paulin D.Biochem. J. 409:657-667(2008) Izard T., Evans G., Borgon R.A.Nature 427:171-175(2004) |