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Antigenic Specificity | ITBP2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of ITBP2 protein. ITGB1BP2 encodes a protein with two cysteine and histidine-rich (CHORD) domains, PXXP motifs, YXXI/P motifs, putative SH2 and SH3 domain binding motifs, and an acidic region at the C-terminus that can bind calcium. Two hybrid analysis showed that this protein interacts with the cytoplasmic domain of the beta 1 integrin subunit and is thought to act as a chaperone protein. Studies in the mouse ortholog of ITGB1BP2 indicate that absence of this gene in mouse results in failed cardiac hypertrophy in response to mechanical stress. Alternative splicing results in multiple transcript variants encoding different isoforms, including an isoform that lacks several domains, including one of the |
Immunogen | Immunogen: Synthesized peptide derived from part region of human ITBP2 protein at amino acid sequence of 10-90 |
Other Names | [Rabbit ITBP2; Integrin beta-1-binding protein 2; Melusin] |
Gene, Accession # | [ITBP2], Gene ID: 26548, NCBI: NP_036410.1, UniProt: Q9UKP3 |
Catalog # | MBS9709547 |
Price | $130, $220, $325 |
Order / More Info | ITBP2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |