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Antigenic Specificity | CASP10 - c-terminal region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against CASP10. It was validated on Western BlotTarget Description: This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Mutations in this gene are associated with type IIA autoimmune lymphoproliferative syndrome, non-Hodgkin lymphoma and gastric cancer. |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the c-terminal region of Human CASP10 |
Other Names | [caspase-10 isoform 1 preproprotein; Caspase-10; caspase-10; caspase 10; Apoptotic protease Mch-4; FAS-associated death domain protein interleukin-1B-converting enzyme 2; FLICE2; ICE-like apoptotic protease 4] |
Gene, Accession # | [CASP10], Gene ID: 843, NCBI: NP_116759, UniProt: Q92851 |
Catalog # | MBS3214149 |
Price | $335 |
Order / More Info | CASP10 - c-terminal region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |