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Antigenic Specificity | IFT57 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Required for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway (By similarity). Has pro-apoptotic function via its interaction with HIP1, leading to recruit caspase-8 (CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5'-AAAGACATG-3' present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator; however the relevance of such function remains unclear. |
Immunogen | Immunogen: Recombinant human Intraflagellar transport protein 57 homolog protein (170-429aa) Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-366022 |
Other Names | [Dermal papilla-derived protein 8; Estrogen-related receptor beta-like protein 1; HIP1-interacting protein; MHS4R2; IFT57; DERP8; ESRRBL1; HIPPI], [IFT57; IFT57; HIPPI; MHS4R2; ESRRBL1; DERP8; ESRRBL1; HIPPI] |
Gene, Accession # | [IFT57], Gene ID: 55081, NCBI: NP_060480.1, UniProt: Q9NWB7 |
Catalog # | MBS1492522 |
Price | $120, $160 |
Order / More Info | IFT57 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |