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Antigenic Specificity | Netrin receptor DCC |
Clone | polyclonal |
Host Species | n/a |
Reactive Species | mouse, human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | n/a |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody is produced by immunizing rabbits with a synthetic peptide (KLH-coupled) corresponding to AIRE. Netrin receptor DCC (deleted colorectal careinoma) was originally identified as a putative tumor suppressor gene that is lost in more than 70% of colorectal cancers. The DCC protein is a type I transmembrane glycoprotein that belongs to the immunoglobulin (Ig) superfamily. It is found in axons of the central and peripheral nervous system and in differentiated cell types of the intestine. Native DCC is found in three isoforms. Two forms, a long and a short isoform, are produced from the same gene but have different initiation sites. The third isoform, produced by alternative splicing, is expressed only in embryonic tissue. Colorectal |
Immunogen | n/a |
Other Names | [netrin receptor DCC; Netrin receptor DCC; netrin receptor DCC; DCC netrin 1 receptor; Colorectal cancer suppressor; Immunoglobulin superfamily DCC subclass member 1; Tumor suppressor protein DCC], [DCC; DCC; CRC18; CRCR1; MRMV1; HGPPS2; IGDCC1; NTN1R1; IGDCC1] |
Gene, Accession # | Gene ID: 1630, NCBI: NP_005206.2, UniProt: P43146 |
Catalog # | MBS857291 |
Price | $280 |
Order / More Info | Netrin receptor DCC Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |