Mouse MDM2 Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | Mouse MDM2 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | n/a |
| Isotype | n/a |
| Format | unconjugated |
| Size | 0.05 mg |
| Concentration | IgG concentration 0.5mg/ml |
| Applications | ELISA (EIA), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This item detects murine Mdm2, a nuclear phosphoprotein that controls intracellular levels of the tumour suppressor protein p53 by ubiquitination and subsequent proteasomal degradation. Mdm2 also interacts with the retinoblastoma (RB) protein and E2F-1, to promote G1-S phase transition in the cell cycle. . . Mdm2 activity is controlled by self-ubiquitination; however activation of the PI3K/PKB pathway leads to phosphorylation of Mdm2 at Ser185, which stabilises the protein. MBS222809 detects murine Mdm2, a nuclear phosphoprotein that controls intracellular levels of the tumour suppressor protein p53 by ubiquitination and subsequent proteasomal degradation. Mdm2 also interacts with the retinoblastoma (RB) protein and E2F-1, to promote G1-S |
| Immunogen | Immunogen: Synthetic peptide corresponding to aa 177-195 of mouse Mdm2. Buffer Solution: Phosphate buffered saline Antiserum Preparation: Antisera to Mdm2 were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography. Target Species: Mouse |
| Other Names | [E3 ubiquitin-protein ligase Mdm2; E3 ubiquitin-protein ligase Mdm2; E3 ubiquitin-protein ligase Mdm2; double minute 2 protein; oncoprotein Mdm2; p53-binding protein Mdm2; transformed mouse 3T3 cell double minute 2; Double minute 2 protein; Oncoprotein Mdm2; p53-binding protein Mdm2], [Mdm2; Mdm2; Mdm-2; AA415488; 1700007J15Rik] |
| Gene, Accession # | [MDM2], Gene ID: 17246, NCBI: NP_001275515.1, UniProt: P23804 |
| Catalog # | MBS222809 |
| Price | $300 |
| Order / More Info | Mouse MDM2 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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