C3c, Human Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityC3c, Human
Clone4
Host SpeciesRat
Reactive Specieshuman
IsotypeIgG2a
Formatunconjugated
Size0.1 mg
Concentrationn/a
ApplicationsImmunoprecipitation (IP)
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DescriptionProduct Description: The monoclonal antibody 4 recognizes the cleaved human C3 fragment C3c. The complement system is an important factor in innate immunity. The third complement component, C3, is central to the classical, alternative and lectin pathways of complement activation. Activation products of the complement cascade contain neo-epitopes that are not present in the individual native components. The synthesis of C3 is tissue-specific and is modulated in response to a variety of stimulatory agents. C3 is the most abundant protein of the complement system with serum protein levels of about 1.3 mg/ml. An inherited deficiency of C3 predisposes the person to frequent bacterial infections. C3 fragments are deposited in tissues at sites of
Immunogenn/a
Other Namesn/a
Gene, Accession #[C3c]
Catalog #MBS584395
Price$520
Order / More InfoC3c, Human Antibody from MYBIOSOURCE INC.
Product Specific References1. Lachmann, P et al; Three monoclonal antibodies to human C3. Immunology 1980, 41: 503 2. Lachmann, P et al; Breakdown of C3 after complement activation. Identification of a new fragment C3g, using monoclonal antibodies. J Exp Med 1982, 156: 205 3. Lachmann, P et al; Use of monoclonal anti-C3 antibodies to characterise the fragments of C3 that are found on erythrocytes. Vox Sang 1983, 45: 367
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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