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Antigenic Specificity | C3c, Human |
Clone | 4 |
Host Species | Rat |
Reactive Species | human |
Isotype | IgG2a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | Immunoprecipitation (IP) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Product Description: The monoclonal antibody 4 recognizes the cleaved human C3 fragment C3c. The complement system is an important factor in innate immunity. The third complement component, C3, is central to the classical, alternative and lectin pathways of complement activation. Activation products of the complement cascade contain neo-epitopes that are not present in the individual native components. The synthesis of C3 is tissue-specific and is modulated in response to a variety of stimulatory agents. C3 is the most abundant protein of the complement system with serum protein levels of about 1.3 mg/ml. An inherited deficiency of C3 predisposes the person to frequent bacterial infections. C3 fragments are deposited in tissues at sites of |
Immunogen | n/a |
Other Names | n/a |
Gene, Accession # | [C3c] |
Catalog # | MBS584395 |
Price | $520 |
Order / More Info | C3c, Human Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Lachmann, P et al; Three monoclonal antibodies to human C3. Immunology 1980, 41: 503 2. Lachmann, P et al; Breakdown of C3 after complement activation. Identification of a new fragment C3g, using monoclonal antibodies. J Exp Med 1982, 156: 205 3. Lachmann, P et al; Use of monoclonal anti-C3 antibodies to characterise the fragments of C3 that are found on erythrocytes. Vox Sang 1983, 45: 367 |