ERK8 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityERK8
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mousepredicted: porcine, zebrafish, bovine, sheep, rabbit, dog, chicken, Xenopus
Isotypen/a
Formatpeptide affinity purified
Size0.05 mL, 0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Peptide ELISA (EIA)
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DescriptionSpecificity: ERK8 Antibody detects endogenous levels of ERK8. Description: In vitro, phosphorylates MBP.Post Translational Modifications: Dually phosphorylated on Thr-175 and Tyr-177, which activates the enzyme. Autophosphorylated on threonine and tyrosine residues in vitro. Ubiquitinated. Ubiquitination may allow its tight kinase activity regulation and rapid turnover. May be ubiquitinated by a SCF E3 ligase (By similarity).Subunit Structure: Interacts with CSK/c-Src, ABL1, RET and TGFB1I1.Similarity: The N-terminal region (1-20) is the minimal region necessary for ubiquitination and further proteasomal degradation. The TXY motif contains the threonine and tyrosine residues whose phosphorylation activates the MAP ki
ImmunogenImmunogen: A synthesized peptide derived from human ERK8. Tissue Specificity: Widely expressed with a maximal expression in lung and kidney.
Other Names[ERK-7; ERK-8; ERK7; ERK8; Extracellular regulated kinase 8 delta; Extracellular signal regulated kinase 8; Extracellular signal-regulated kinase 7; Extracellular signal-regulated kinase 8; MAP kinase 15; MAPK 15; Mapk15; Mitogen activated protein kinase 15; Mitogen-activated protein kinase 15; MK15_HUMAN]
Gene, Accession #[ERK8], Gene ID: 225689, NCBI: NP_620590.2, UniProt: Q8TD08
Catalog #MBS9611211
Price$225, $280, $340
Order / More InfoERK8 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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