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Antigenic Specificity | Hsp90 (P. Falciparum) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | It is specific to P.falciparum and does not cross-react to Hsp90 from human, yeast, and dictyostelium. |
Isotype | n/a |
Format | unconjugated |
Size | 0.025 mg |
Concentration | 1mg/mL |
Applications | Western Blot (WB), Immunofluorescence (IF), Co-IP |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Background Info: This protein A Affinity purified antibody detects an 86kD protein, corresponding to P.falciparum Hsp90 on SDS PAGE immunoblot; in samples from P.Falciparum origin. Scientific Background: HSP90 is an abundantly and ubiquitously expressed heat shock protein. It is understood to exist in two principal forms alpha and beta, which share 85% sequence amino acid homology. The two isoforms of Hsp90 are expressed in the cytosolic compartment (1). Despite the similarities, HSP90alpha exists predominantly as a homodimer while HSP90beta exists mainly as a monomer.(2) From a functional perspective, hsp90 participates in the folding, assembly, maturation, and stabilization of specific proteins as an integral component of a chaperone comp |
Immunogen | n/a |
Other Names | [PF14_0417 HSP90; PfHsp90], [PF14_0417] |
Gene, Accession # | Gene ID: 811999, NCBI: XP_001348591.1, UniProt: Q8IL32 |
Catalog # | MBS805002 |
Price | $250 |
Order / More Info | Hsp90 (P. Falciparum) Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Nemoto, T. et al. (1997) J.Biol Chem. 272, 26179-26187. 2. Minami, Y, et al. (1991), J.Biol Chem. 266, 10099-10103. 3. Arlander SJH, et al. (2003) J Biol Chem 278, 52572-52577. 4. Pearl H, et al. (2001) Adv Protein Chem 59,157-186. 5. Neckers L, et al. (2002) Trends Mol Med 8:S55-S61. 6. Pratt W, Toft D. (2003) Exp Biol Med 228:111-133. 7. Pratt W, Toft D. (1997) Endocr Rev 18,306-360. 8. Pratt WB. (1998) Proc Soc Exptl Biol Med 217, 420-434. 9. Whitesell L, et al. (1994) Proc Natl Acad Sci USA 91, 8324-8328. 10. Banumathy G., Singh V., Pavithra S.R., and Tatu U.(2003) J Biol Chem. 278(20):18336-45. 11. Pavithra S.R, Banumathy G., Joy O., Singh V., and Tatu U. (2004) J Biol Chem. 279(45):46692-9. |