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Antigenic Specificity | GRK (pan) |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | Immunoblot, Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody recognizes human, mouse and rat GRK5. It cross-reacts with GRK6. G protein-coupled receptor kinases (GRK) are serine/threonine kinases that phosphorylate a variety of activated G-protein-coupled receptors (GPCRs) including adrenergic receptors, muscarinic acetylcholine receptors, dopamine receptors, and opioid receptors. GRK receptor phosphorylation initiates beta-arrestin-mediated receptor desensitization, internalization, and signaling events leading to their down-regulation. |
Immunogen | Immunogen: Fusion protein corresponding to aa 381-590 (C-terminus) of mouse GRK5. This sequence is 91% identical to human, 99% identical to rat, >55% identical to GRK6 and GRK4, and >40% identical to GRK7 and RK. |
Other Names | [G protein-coupled receptor kinase 5; G protein-coupled receptor kinase 5; G protein-coupled receptor kinase 5; G protein-coupled receptor kinase 5; G protein-coupled receptor kinase GRK5], [Grk5; Grk5; Gprk5; Gprk5] |
Gene, Accession # | [GRK], Gene ID: 14773, NCBI: NP_061357.3, UniProt: Q8VEB1 |
Catalog # | MBS191342 |
Price | $410 |
Order / More Info | GRK (pan) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |