GRK (pan) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityGRK (pan)
Clonemonoclonal
Host SpeciesMouse
Reactive Speciesn/a
IsotypeIgG1
Formatunconjugated
Size0.1 mg
Concentrationn/a
ApplicationsImmunoblot, Immunofluorescence (IF)
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DescriptionThis antibody recognizes human, mouse and rat GRK5. It cross-reacts with GRK6. G protein-coupled receptor kinases (GRK) are serine/threonine kinases that phosphorylate a variety of activated G-protein-coupled receptors (GPCRs) including adrenergic receptors, muscarinic acetylcholine receptors, dopamine receptors, and opioid receptors. GRK receptor phosphorylation initiates beta-arrestin-mediated receptor desensitization, internalization, and signaling events leading to their down-regulation.
ImmunogenImmunogen: Fusion protein corresponding to aa 381-590 (C-terminus) of mouse GRK5. This sequence is 91% identical to human, 99% identical to rat, >55% identical to GRK6 and GRK4, and >40% identical to GRK7 and RK.
Other Names[G protein-coupled receptor kinase 5; G protein-coupled receptor kinase 5; G protein-coupled receptor kinase 5; G protein-coupled receptor kinase 5; G protein-coupled receptor kinase GRK5], [Grk5; Grk5; Gprk5; Gprk5]
Gene, Accession #[GRK], Gene ID: 14773, NCBI: NP_061357.3, UniProt: Q8VEB1
Catalog #MBS191342
Price$410
Order / More InfoGRK (pan) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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