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Antigenic Specificity | IRAKM |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, Immunocytochemistry (ICC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Rabbit IgG polyclonal antibody for Interleukin-1 receptor-associated kinase 3(IRAK3) detection. Tested with WB, IHC-P, ICC in Human, Mouse, Rat. Background: Interleukin-1 receptor-associated kinase 3, also called IRAK3 or IRAKM is an enzyme that in humans is encoded by the IRAK3 gene. The IRAKM gene consists of 12 exons spanning a region of approximately 60 kb in chromosome 12q14.3. This gene encodes a member of the interleukin-1 receptor-associated kinase protein family. Members of this family are essential components of the Toll/IL-R immune signal transduction pathways. This protein is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. Mutations in this gene |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of mouse IRAKM (349-364aa KHLWYMPEEYIRQGRL), identical to the related rat sequence, and different from the related human sequence by one amino acid. |
Other Names | [Interleukin-1 receptor-associated kinase 3; interleukin-1 receptor-associated kinase 3; ASRT5; IL 1 receptor associated kinase M; IL-1 receptor-associated kinase M; IL1 receptor associated kinase M; Interleukin 1 receptor associated kinase 3; Interleukin 1 receptor associated kinase M; Interleukin-1 receptor-associated kinase 3; IRAK 3; IRAK M; IRAK-3; IRAK-M; IRAK3; IRAK3_HUMAN], [Irak3; Irak3; IRAK-M; AI563835; 4833428C18Rik; IRAK-3; IRAK-M] |
Gene, Accession # | [IRAK3], Gene ID: 73914, NCBI: Q8K4B2.2, UniProt: Q8K4B2 |
Catalog # | MBS176957 |
Price | $315 |
Order / More Info | IRAKM Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |