PEK/PERK (Ab-981) Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | PEK/PERK (Ab-981) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.05 mL, 0.1 mL |
| Concentration | 1.0 mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The antibody detects endogenous levels of total PEK/PERK protein. Phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2), leading to its inactivation and thus to a rapid reduction of translational initiation and repression of global protein synthesis. Serves as a critical effector of unfolded protein response (UPR)-induced G1 growth arrest due to the loss of cyclin-D1 (CCND1) By similarity.Shi Y., J. Biol. Chem. 274:5723-5730(1999).Sood R., Biochem. J. 346:281-293(2000).Delepine M., Nat. Genet. 25-406-409(2000). |
| Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized non-phosphopeptide derived from human PEK/PERK around the phosphorylation site of threonine 981 (R-H-T(p)-G-Q). |
| Other Names | [E2AK3; EC 2.7.11.1; EIF2AK3; Eukaryotic translation initiation factor 2-alpha kinase 3 precursor; HsPEK] |
| Gene, Accession # | [PEK/PERK], Gene ID: 9451, NCBI: NP_004827.4, UniProt: Q9NZJ5 |
| Catalog # | MBS9408865 |
| Price | $200, $255 |
| Order / More Info | PEK/PERK (Ab-981) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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