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Antigenic Specificity | SUN2 |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG |
Format | unconjugated |
Size | 0.02 mL, 0.05 mL, 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunoprecipitation (IP), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | SUN1 (MIM 607723) and SUN2 are inner nuclear membrane (INM) proteins that play a major role in nuclear-cytoplasmic connection by formation of a 'bridge' across the nuclear envelope, known as the LINC complex, via interaction with the conserved luminal KASH domain of nesprins located in the outer nuclear membrane (ONM). The LINC complex provides a direct connection between the nuclear lamina and the cytoskeleton, which contributes to nuclear positioning and cellular rigidity. |
Immunogen | Source Note: This monoclonal antibody is produced by immunizing mice with a sythetic peptide(KLH coupled)corresponding to amino-terminal residues of human SUN2 |
Other Names | [nuclear envelope protein; Protein unc-84 homolog B; Rab5-interacting protein; Rab5IP; Sad1 unc-84 domain protein 2; Sad1/unc-84 protein-like 2; SUN domain-containing protein 2; unc-84 homolog B; FRIGG; KIAA0668; RAB5IP; SUN2; UNC84B], [SUN2; SUN2; UNC84B; FRIGG; KIAA0668; RAB5IP; UNC84B; Rab5IP] |
Gene, Accession # | [SUN2], Gene ID: 25777, NCBI: NP_001186508.1, UniProt: Q9UH99 |
Catalog # | MBS435149 |
Price | $225, $350, $565 |
Order / More Info | SUN2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |