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Antigenic Specificity | BECN1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | Protein G purified |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Plays a central role in autophagy (PubMed: 23184933). Acts as core subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate; different complex forms are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis. Involved in regulation of degradative endocytic trafficking and required for the abcission step in cytokinesis, probably in the context of PI3KC3-C2 (PubMed: 20643123, PubMed: 20208530). Essential for the formation of PI3KC3-C2 but not PI3KC3-C1 PI3K complex forms. Involved in endocytosis (PubMed: 25275521). Protects against infection by a neurovirulent strain of Sindbis virus (P |
Immunogen | Immunogen: Recombinant Human Beclin-1 protein (1-100AA) |
Other Names | [Beclin-1; Coiled-coil myosin-like BCL2-interacting protein; Protein GT197; Beclin-1-C 35 kDa; BECN1; GT197] |
Gene, Accession # | [BECN1], Gene ID: 8678, NCBI: NP_001300927.1, UniProt: Q14457 |
Catalog # | MBS7050160 |
Price | $160, $235 |
Order / More Info | BECN1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |