SP100 - C-terminal region Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | SP100 - C-terminal region |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | mouse |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Together with PML, this tumor suppressor is a major constituent of the PML bodies, a subnuclear organelle involved in a large number of physiological processes including cell growth, differentiation and apoptosis. Functions as a transcriptional coactivator of ETS1 and ETS2. Under certain conditions, it may also act as a corepressor of ETS1 preventing its binding to DNA. Through the regulation of ETS1 it may play a role in angiogenesis, controlling endothelial cell motility and invasion. Through interaction with the MRN complex it may be involved in the regulation of telomeres lengthening. May also regulate TP53-mediated transcription and through CASP8AP2, regulate FAS-mediated apoptosis. May also play a role in infection by viruses through |
| Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of mouse SP100 |
| Other Names | [nuclear autoantigen Sp-100 isoform 2; Nuclear autoantigen Sp-100; nuclear autoantigen Sp-100; nuclear antigen Sp100; Nuclear dot-associated Sp100 protein; Speckled 100 kDa] |
| Gene, Accession # | [SP100], Gene ID: 20684, NCBI: NP_001300641.1, UniProt: O35892 |
| Catalog # | MBS3224245 |
| Price | $335 |
| Order / More Info | SP100 - C-terminal region Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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