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Antigenic Specificity | INSIG1 - middle region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | cow, dog, goat, guinea pig, horse, human, mouse, porcine, rabbit, rat, sheep, zebrafish |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against INSIG1. It was validated on Western Blot using a cell lysate as a positive control.Target Description: Oxysterols regulate cholesterol homeostasis through the liver X receptor (LXR)- and sterol regulatory element-binding protein (SREBP)-mediated signaling pathways. This gene is an insulin-induced gene. INSIG1 is an endoplasmic reticulum (ER) membrane protein that plays a critical role in regulating cholesterol concentrations in cells. INSIG1 binds to the sterol-sensing domains of SREBP cleavage-activating protein (SCAP) and HMG CoA reductase, and is essential for the sterol-mediated trafficking of the two proteins.The protein encoded by this gene is highly similar to the protein product e |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human INSIG1 |
Other Names | [insulin-induced gene 2 protein isoform a; Insulin-induced gene 2 protein; insulin-induced gene 2 protein; insulin induced gene 2] |
Gene, Accession # | [INSIG2], Gene ID: 51141, NCBI: NP_057217, UniProt: Q9Y5U4 |
Catalog # | MBS3205038 |
Price | $365 |
Order / More Info | INSIG1 - middle region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |