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Antigenic Specificity | MAPK8IP1/JIP1 (aa69-118) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | humanpredicted: mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Immunofluorescence (IF), Immunohistochemistry (IHC) Paraffin, Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: JIP1 (Ab-103) Antibody detects endogenous levels of total JIP1 protein. The JNK-interacting protein (JIP) group of scaffold protein sselectively mediates JNK signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module. Required for JNK activation in response to excitotoxic stress. CytoplasmicMAPK8IP1 causes inhibition of JNK-regulated activity by retaining JNK in the cytoplasm and inhibiting JNK phosphorylation of c-Jun. May alsoparticipate in ApoER2-specific reelin signaling. |
Immunogen | Immunogen: Synthetic peptide from human JIP1 (aa69-118). Conjugation: Unconjugated |
Other Names | [Rabbit to Human MAPK8IP1/JIP1; MAPK8IP1; JIP1; JNK-interacting protein 1; IB-1; IB1; Islet-brain 1; JIP-1; PRKM8 interacting protein; PRKM8IP] |
Gene, Accession # | [MAPK8IP1/JIP1], Gene ID: 9479, NCBI: NP_005447.1, UniProt: Q9UQF2 |
Catalog # | MBS2401175 |
Price | $615 |
Order / More Info | MAPK8IP1/JIP1 (aa69-118) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |