Edit |   |
---|---|
Antigenic Specificity | Human MUSCARINIC RECEPTOR M3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse (expected from sequence) |
Isotype | n/a |
Format | unconjugated |
Size | 0.05 mg |
Concentration | IgG concentration 0.5 mg/ml |
Applications | Immunohistology Paraffin* |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This item detects the muscarinic receptor M3, a G protein-coupled receptor for acetylcholine which is expressed in smooth muscle and glandular tissues. The M3 subtype is coupled to other G proteins known as Go or Gq which activate phospholipase C leading to an increase in intracellular Ca2+.. . The M3 muscarinic receptor controls smooth muscle contraction in blood vessels and lungs as well as in the gastrointestinal tract. It is also located in many glands, and its activation helps to stimulate secretion. MBS222839 detects the muscarinic receptor M3, a G protein-coupled receptor for acetylcholine which is expressed in smooth muscle and glandular tissues. The M3 subtype is coupled to other G proteins known as Go or Gq which activate phosph |
Immunogen | Immunogen: Synthetic peptide: 3rd cytoplasmic domain of human muscarinic receptor M3, conjugated to Keyhole Limpet Hemocyanin (KLH) Histology Positive Control Tissue: Brain, cortex. Buffer Solution: Phosphate buffered saline Antiserum Preparation: Antisera to human muscarinic receptor M3 were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography. Target Species: Human |
Other Names | [muscarinic acetylcholine receptor M3; Muscarinic acetylcholine receptor M3; muscarinic acetylcholine receptor M3; acetylcholine receptor, muscarinic 3; m3 muscarinic receptor; cholinergic receptor, muscarinic 3], [CHRM3; CHRM3; HM3; EGBRS] |
Gene, Accession # | Gene ID: 1131, NCBI: NP_000731.1, UniProt: P20309 |
Catalog # | MBS222839 |
Price | $550 |
Order / More Info | Human MUSCARINIC RECEPTOR M3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |