Human IRAK3 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman IRAK3
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciesmouse, rat
Isotypen/a
Formatunconjugated
Size0.1 mg
ConcentrationIgG concentration 0.5 mg/ml
ApplicationsImmunohistology Paraffin*, Western Blot (WB)
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DescriptionRabbit anti Human IRAK3 antibody recognizes human Interleukin-1 receptor-associated kinase 3 (IRAK3), a member of the IRAK/Pelle family. IRAKs associate with the IL1/Toll receptors after IL-1 or LPS stimulation, thereby playing an important role in the inflammatory response. IRAK3 inhibits the dissociation of IRAK1 and IRAK4 from the Toll-like receptor signalling complex by either inhibiting the phosphorylation of IRAK1 and IRAK4 or stabilising the receptor complex. It is predominantly expressed in peripheral blood lymphocytes. Defects in the IRAK3 gene are associated with susceptibility to asthma-related traits type 5. Rabbit anti Human IRAK3 antibody does not cross-react with IRAK or IRAK2.
ImmunogenImmunogen: Peptide corresponding to amino acids from the carboxy terminus of human IRAK3. Buffer Solution: Phosphate buffered saline Antiserum Preparation: Antisera to human IRAK3 were raised by repeated immunisation of rabbits with highly purified antigen. Target Species: Human
Other Names[interleukin-1 receptor-associated kinase 3 isoform b; Interleukin-1 receptor-associated kinase 3; interleukin-1 receptor-associated kinase 3; IL-1 receptor-associated kinase M; IRAK3; interleukin-1 receptor-associated kinase 3; IL-1 receptor-associated kinase M; IRAK-M], [IRAK3; IRAK3; ASRT5; IRAKM; IRAK-3; IRAK-M]
Gene, Accession #[IRAK3], Gene ID: 11213, NCBI: NP_001135995.1, UniProt: Q9Y616
Catalog #MBS223357
Price$375
Order / More InfoHuman IRAK3 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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