Edit |   |
---|---|
Antigenic Specificity | PKD1/2/3/PKC u (Phospho-Ser738/742) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | epitope affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of PKD1/2/3/PKC mu only when phosphorylated at Serine 738/742. Serine/threonine-protein kinase that converts transient diacylglycerol (DAG) signals into prolonged physiological effects downstream of PKC, and is involved in the regulation of MAPK8/JNK1 and Ras signaling, Golgi membrane integrity and trafficking, cell survival through NF-kappa-B activation, cell migration, cell differentiation by mediating HDAC7 nuclear export, cell proliferation via MAPK1/3 (ERK1/2) signaling, and plays a role in cardiac hypertrophy, VEGFA-induced angiogenesis, genotoxic-induced apoptosis and flagellin-stimulated inflammatory response. Phosphorylates the epidermal growth factor receptor (EGFR) on dual threonine residues, |
Immunogen | Immunogen Type: Peptide-KLH Immunogen Description: Peptide sequence around phosphorylation site of Serine738/Serine 742 |
Other Names | [PKD, PKCM, PRKCM, PKC-MU] |
Gene, Accession # | [PKD1/2/3/PKC u], Gene ID: 5587, NCBI: NP_002733.2, UniProt: Q15139 |
Catalog # | MBS9414438 |
Price | $200, $255 |
Order / More Info | PKD1/2/3/PKC u (Phospho-Ser738/742) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |