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Antigenic Specificity | GCN5L2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: GCN5L2 antibody detects endogenous levels of total GCN5L2. Function: Protein lysine acyltransferase that can act both as a acetyltransferase and succinyltransferase, depending on the context (PubMed:29211711). Acts as a histone lysine succinyltransferase: catalyzes succinylation of histone H3 on 'Lys-79' (H3K79succ), with a maximum frequency around the transcription start sites of genes (PubMed:29211711). Succinylation of histones gives a specific tag for epigenetic transcription activation (PubMed:29211711). Association with the 2-oxoglutarate dehydrogenase complex, which provides succinyl-CoA, is required for histone succinylation (PubMed:29211711). In different complexes, functions either as an acetyltransferase (HAT) or as |
Immunogen | Immunogen: A synthesized peptide Subcellular Location: Nucleus. Tissue Specificity: Expressed in all tissues tested, with most abundant expression in ovary. Predicted Cross Reactivity: Pig, Zebrafish, Bovine, Horse, Sheep, Dog, Chicken Similarity: Pig (100%), Zebrafish (91%), Bovine (100%), Horse (100%), Sheep (100%), Dog (100%), Chicken (100%) |
Other Names | [1110051E14Rik; AW212720; EC 2.3.1.48; GCN 5; GCN5 (general control of amino-acid synthesis, yeast, homolog)-like 2; Gcn5; GCN5 general control of amino-acid synthesis 5-like 2 (yeast); GCN5L2; general control of amino acid synthesis 5-like 2; General control of amino acid synthesis protein 5-like 2; General control of amino acid synthesis, yeast, homolog-like 2; HGCN5; Histone acetyltransferase GCN5; Histone acetyltransferase KAT2A; hsGCN5; K(lysine) acetyltransferase 2A; KAT2 A; KAT2A; KAT2A_HUMAN; Lysine acetyltransferase 2A; MGC102791; PCAF-b; STAF97] |
Gene, Accession # | [GCN5L2], Gene ID: 2648, NCBI: NP_066564.2, UniProt: Q92830 |
Catalog # | MBS9604844 |
Price | $240, $280 |
Order / More Info | GCN5L2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |