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Antigenic Specificity | WDR5 |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: WDR5 antibody detects endogenous levels of total WDR5. Description: WD-repeat protein 5 (WDR5, also designated BMP-2-induced gene 3 kb or BIG-3) belongs to the family of WD-40 repeat proteins, and is essential for vertebrate development, Hox gene activation and global H3K4 trimethylation. WDR5 is a conserved subunit of Trithorax (TRX) histone methyltransferase complexes that selectively binds to dimethylated Lys4 (K4me2) in Histone H3 to promote K4 trimethylation by TRX. It is expressed in osteoblasts, chondrocytes, osteocytes and marrow stromal cells. The WDR5 protein contains 7 WD-repeats, which may play a role in its function of accelerating osteoblast differentiation.Function: Contributes to histone modification. May po |
Immunogen | Immunogen: Purified recombinant fragment of human WDR5 expressed in E. Coli Subcellular Location: Nucleus. |
Other Names | [2410008O07Rik; AA408785; AA960360; BIG 3; Big; BIG3; BMP2 induced 3 kb gene protein; BMP2 induced gene, 3-KB; BMP2-induced 3-kb gene protein; MGC114572; OTTHUMP00000162494; SWD 3; SWD3; SWD3 Set1c WD40 repeat protein homolog; WD repeat containing protein 5; WD repeat domain 5; WD repeat protein 5; WD repeat-containing protein 5; WD repeat-containing protein BIG-3; WDR 5; Wdr5; WDR5_HUMAN] |
Gene, Accession # | [WDR5], Gene ID: 11091, NCBI: NP_060058.1, UniProt: P61964 |
Catalog # | MBS9602687 |
Price | $235, $295, $370 |
Order / More Info | WDR5 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |