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Antigenic Specificity | LMOD3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: LMOD3 antibody detects endogenous levels of LMOD3. Function: Essential for the organization of sarcomeric actin thin filaments in skeletal muscle (PubMed:25250574). Increases the rate of actin polymerization (PubMed:25250574).Subunit Structure: May interact with tropomyosin alpha (TPM1/2) N-terminus (PubMed:25250574). Interacts with KLHL40; leading to stabilization (By similarity).Post-translational Modifications: Ubiquitinated, leading to its degradation. Interaction with KLHL40 negatively regulates ubiquitination and degradation.Similarity: Belongs to the tropomodulin family. |
Immunogen | Immunogen: A synthesized peptide derived from human LMOD3. Subcellular Location: Cytoplasm > Cytoskeleton. Tissue Specificity: Expressed in cardiac and at higher levels in skeletal muscles (at protein level). |
Other Names | [fetal form; Leiomodin; Leiomodin-3; LMOD3; LMOD3_HUMAN] |
Gene, Accession # | [LMOD3], Gene ID: 56203, NCBI: NP_001291347.1, UniProt: Q0VAK6 |
Catalog # | MBS9603285 |
Price | $240, $280 |
Order / More Info | LMOD3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |