Mouse CD71 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMouse CD71
Clone[RI7217]
Host SpeciesRat
Reactive Speciesmouse
IsotypeIgG2a kappa
Formatunconjugated
Size0.5 mg
Concentrationn/a
ApplicationsFlow Cytometry; Immunoprecipitation
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DescriptionSpecificity: CD71/transferrin receptor, Mr 180-190 kDa (90-95 kDa under reducing conditions). CD71, a type II transmembrane glycoprotein expressed on the cell surface as a homodimer, is the transferrin receptor. It is essential for the growth of normal and neoplastic cells.^1, 4 It is expressed at low levels on resting B and T lymphocytes but is upregulated during responses to antigens and mitogens, presumably reflecting the iron dependence of proliferation.^4 Its expression declines with maturation and differentiation. CD71 plays a critical role in cell proliferation by controlling the supply of iron, which is essential for many metabolic pathways, through the binding and endocytosis of transferrin, the major ironcarrying protein. It may a
Immunogenn/a
Other Namesn/a
Gene, Accession #n/a
Catalog #MBS673434
Price$260
Order / More InfoMouse CD71 Antibody from MYBIOSOURCE INC.
Product Specific References1. Lesley, J., R. Hyman, R. Schulte, and J. Trotter. 1984. Cell Immunol. 83:14.2. Kemp, J. D., J. A. Thorson, F. Gomez, K. M. Smith, J. S. Cowdery, and Z. K. Ballas. 1989. Cell Immunol. 122:218.3. Lesley, J.F., and R.J. Schulte. 1985. Mol. Cell. Biol. 5:1814.4. Kemp, J. D., J. A. Thorson, T. H. McAlmont, M. Horowitz, J. S. Cowdery, and Z. K. Ballas. 1987. J. Immunol. 138:2422.5. Sauvage, C.A., J.C. Mendelsohn, J.F. Lesley, and I.S. Trowbridge. 1987. Cancer Res. 47:747.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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