NDP - middle region Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | NDP - middle region |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | cow, dog, guinea pig, horse, human, mouse, rabbit, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Immunohistochemistry (IHC), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This is a rabbit polyclonal antibody against NDP. It was validated on Western Blot using a cell lysate as a positive control.Target Description: NDP activates the canonical Wnt signaling pathway through FZD4 and LRP5 coreceptor. NDP plays a central role in retinal vascularization by acting as a ligand for FZD4 that signals via stabilizing beta-catenin (CTNNB1) and activating LEF/TCF-mediated transcriptional programs. NDP acts in concert with TSPAN12 to activate FZD4 independently of the Wnt-dependent activation of FZD4, suggesting the existence of a Wnt-independent signaling that also promote accumulation the beta-catenin (CTNNB1). NDP may be involved in a pathway that regulates neural cell differentiation and proliferation. NDP is |
| Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human NDP |
| Other Names | [norrin; Norrin; norrin; norrin cystine knot growth factor NDP; Norrie disease protein; X-linked exudative vitreoretinopathy 2 protein] |
| Gene, Accession # | [NDP], Gene ID: 4693, NCBI: NP_000257, UniProt: Q00604 |
| Catalog # | MBS3212550 |
| Price | $365 |
| Order / More Info | NDP - middle region Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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