CD103/Integrin alpha E (T-Cell Lymphoma & Hairy Cell Leukemia Marker) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | CD103/Integrin alpha E (T-Cell Lymphoma & Hairy Cell Leukemia Marker) |
| Clone | [ITGAE/2063] |
| Host Species | Mouse |
| Reactive Species | human. |
| Isotype | IgG2c, kappa |
| Format | unconjugated |
| Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
| Concentration | n/a |
| Applications | Immunohistochemistry (IHC) Formalin |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This MAb recognizes a protein of 150kDa, identified as CD103, which is the alpha-E integrin subunit of the heterodimeric alpha-E beta-7 (aEb7) integrin belonging to a small beta-7 integrin subfamily. CD103 is expressed on more than 95% of intraepithelial CD8+ cells and on 40% of mucosa-associated T cells, whereas less than 2% of resting blood lymphocytes are CD103-positive. In several malignant conditions, such as T-cell lymphomas and hairy cell leukemia (HCL), the cells express CD103. Antibody to CD103 is an extremely useful addition to the IHC panel for the diagnosis of hairy cell leukemia (HCL). |
| Immunogen | Immunogen: Recombinant human ITGAE protein fragment Cellular Localization: Cell Surface and Cytoplasmic |
| Other Names | [CD103; Human mucosal lymphocyte antigen 1 (HML1 antigen); Integrin alpha E heavy chain; Integrin alpha E light chain; Integrin alpha E; epithelial-associated; Integrin alpha E1; Integrin alpha-IEL (intestinal intraepithelial lymphocytes); Integrin alpha M290; Integrin alpha-E heavy chain; Integrin; alpha E (ITGAE)] |
| Gene, Accession # | [CD103], Gene ID: 3682, NCBI: NP_002199.3, UniProt: P38570 |
| Catalog # | MBS4380452 |
| Price | $190, $340, $340 |
| Order / More Info | CD103/Integrin alpha E (T-Cell Lymphoma & Hairy Cell Leukemia Marker) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Morgan EA, Yu H, Pinkus JL, Pinkus GS. Immunohistochemical detection of hairy cell leukemia in paraffin sections using a highly effective CD103 rabbit monoclonal antibody. Am J Clin Pathol. 2013 Feb; 139(2):220-30. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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