Human Methionine Adenosyltransferase II Alpha Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human Methionine Adenosyltransferase II Alpha |
| Clone | [PAT3A2AT] |
| Host Species | Mouse |
| Reactive Species | n/a |
| Isotype | IgG2b k |
| Format | Protein G purified |
| Size | 0.005 mg, 0.02 mg, 0.1 mg |
| Concentration | n/a |
| Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Introduction: MAT2A is an important enzyme in cellular metabolism and catalyzes the formation of S-adenosylmethionine (SAMe) from L-methionine and ATP. MAT2A is expressed in extrahepatic tissues. In liver, MAT2A expression associates with growth, dedifferentiation, and cancer. NF-kappa B and AP-1 are necessary for basal MAT2A expression in HepG2 cells and mediate the increase in MAT2A expression in response to TNF-alpha. Up-regulation of MAT2A provides growth improvement and s-adenosylmethionine and methylthioadenosine thus can block mitogenic signaling in colon cancer cells. Lower expression of both MAT2A and MAT2beta and interfere with leptin signaling in liver cancer cells. |
| Immunogen | Immunogen: Anti-human MAT2A mAb is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant human MAT2A amino acids 1-395 purified from E Coli. |
| Other Names | [MAT2A; Methionine Adenosyltransferase II Alpha, Mouse Human; MATA2; MATII; SAMS2; MAT-2A; S-adenosylmethionine synthetase isoform type-2; AdoMet synthetase 2; Methionine adenosyltransferase 2; Methionine adenosyltransferase II; MAT2A; AMS2], [MAT2A; MAT2A; MATA2; MATII; SAMS2; AMS2; MATA2; AdoMet synthase 2; MAT 2; MAT-II] |
| Gene, Accession # | [MAT2A], Gene ID: 4144, NCBI: NP_005902.1 |
| Catalog # | MBS140284 |
| Price | $140, $205, $505 |
| Order / More Info | Human Methionine Adenosyltransferase II Alpha Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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