HP1beta Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-HP1beta antibody, protein, ELISA kits.
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| Antigenic Specificity | HP1beta |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Heterochromatin protein 1 (HP1) is a family of heterochromatic adaptor molecules involved in both gene silencing and higher order chromatin structure (1). All three HP1 family members (alpha, beta, and gamma) are primarily associated with centromeric heterochromatin; however, HP1beta and gamma also localize to euchromatic sites in the genome (2, 3). HP1 proteins are approximately 25 kDa in size and contain a conserved amino-terminal chromodomain, followed by a variable hinge region and a conserved carboxy-terminal chromoshadow domain. The chromodomain facilitates binding to histone H3 tri-methylated at Lys9, a histone mark closely associated with centromeric heterochromatin (4, 5). The variable hinge region binds both RNA and DNA in a seq |
| Immunogen | Immunogen: Fusion protein of human CBX1 Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Other Names | [CBX; HP1-BETA; HP1Hs-beta; HP1Hsbeta; M31; MOD1; p25beta] |
| Gene, Accession # | [HP1beta], Gene ID: 10951, NCBI: NP_001120700.1, UniProt: P83916 |
| Catalog # | MBS8501611 |
| Price | $310 |
| Order / More Info | HP1beta Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Maison, C. and Almouzni, G. (2004) Nat. Rev. Mol. Cell Biol. 5, 296-304. 2. Minc, E. et al. (2000) Cytogenet. Cell Genet. 90, 279-284. 3. Nielsen, A.L. et al. (2001) Mol. Cell 7, 729-739. 4. Lachner, M. et al. (2001) Nature 410, 116-120. 5. Bannister, A.J. et al. (2001) Nature 410, 120-124. 6. Muchardt, C. et al. (2002) EMBO Rep. 3, 975-981. 7. Yamamoto, K. and Sonoda, M. (2003) Biochem. Biophys. Res. Commun. 301, 287-292. 8. Fuks, F. et al. (2003) Nucleic Acids Res. 31, 2305-2312. 9. Murzina, N. et al. (1999) Mol. Cell 4, 529-540. 10. Nielsen, S.J. et al. (2001) Nature 412, 561-565. 11. Ogawa, H. et al. (2002) Science 296, 1132-1136. 12. Minc, E. et al. (1999) Chromosoma 108, 220-234. 13. Zhao, T. et al. (2001) J. Biol. Chem. 276, 9512-9518. 14. Lomberk, G. et al. (2006) Nat. Cell Biol. 8, 407-415. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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