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Antigenic Specificity | ADCY8 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: ADCY8 antibody detects endogenous levels of total ADCY8. Function: This is a membrane-bound, calcium-stimulable adenylyl cyclase. May be involved in learning, in memory and in drug dependence (By similarity).Similarity: The protein contains two modules with six transmembrane helices each; both are required for catalytic activity. Isolated N-terminal or C-terminal guanylate cyclase domains have no catalytic activity, but when they are brought together, enzyme activity is restored. The active site is at the interface of the two domains. Both contribute substrate-binding residues, but the catalytic metal ions are bound exclusively via the N-terminal guanylate cyclase domain. Belongs to the adenylyl cyclase class-4/guanylyl cyc |
Immunogen | Immunogen: A synthesized peptide Subcellular Location: Cell Membrane; Multipass Membrane Protein Tissue Specificity: Detected in brain cortex. Predicted Cross Reactivity: Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus Similarity: Pig (100%), Zebrafish (100%), Bovine (100%), Horse (100%), Sheep (100%), Rabbit (100%), Dog (100%), Chicken (100%), Xenopus (100%) |
Other Names | [ADCY3; Adenylate cyclase 8; Adenylate cyclase type VIII; Adenylyl cyclase 8 brain; ATP pyrophosphate-lyase 8; Brain adenylate cyclase 8; Ca(2+)/calmodulin activated adenylyl cyclase; EC 4.6.1.1; HBAC1] |
Gene, Accession # | [ADCY8], Gene ID: 114, NCBI: NP_001106.1, UniProt: P40145 |
Catalog # | MBS9603807 |
Price | $240, $280 |
Order / More Info | ADCY8 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |