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Antigenic Specificity | beta-Actin [10B7] |
Clone | [10B7] |
Host Species | Mouse |
Reactive Species | human, mouse, rat, rabbit, chicken, zebrafish, Drosophila |
Isotype | IgG |
Format | biotin conjugate |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: beta-Actin antibody is human, mouse, rat, rabbit, chicken, zebrafish and drosophila reactive. Actins are highly conserved proteins that are involved in cell motility, structure and integrity, processes that are crucial for tissue development and the development of organism. The actin cytoskeleton is one of the principal drivers of cell motility and is capable of responding to complex signaling cascades. Recent evidence suggests that it may play key roles in regulating apoptosis and aging. Beta actin is one of six different actin isoforms which have been identified. Like GAPDH, beta-Actin is constitutively expressed at high levels in almost all tissues and cell lines making it ideal for use as a loading control marker in immunob |
Immunogen | Immunogen: beta-Actin antibody was raised against a synthetic peptide containing 16 amino acids near the carboxy terminus of beta-actin. Buffer: beta-Actin antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [Biotin-Actin; Beta-Actin; Actin; actin, beta], [ACTB; ACTB; BRWS1; PS1TP5BP1] |
Gene, Accession # | [ACTB], Gene ID: 60, NCBI: AAH02409, UniProt: P60709 |
Catalog # | MBS154513 |
Price | $375 |
Order / More Info | beta-Actin [10B7] Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Lambrechts A, Van Troys, M and Ampe C. The actin cytoskeleton in normal and pathological cell motility. Int. J. Biochem. Cell Biol. 2004; 36:1890-909. 2. Gourlay CW and Ayscough KR. The actin cytoskeleton: a key regulator of apoptosis and ageing. Nat. Rev. 2005; 6:583-9. |