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Antigenic Specificity | Caspase-2 |
Clone | monoclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | IgG |
Format | unconjugated |
Size | 0.05 mL, 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Caspase 2 also known as CASP2 is an enzyme that, in humans, is encoded by the CASP2 gene. Caspase 2 proteolytically cleaves other proteins. It belongs to a family of cysteine proteases called caspases that cleave proteins only at an amino acid following an aspartic acid residue. Within this family, caspase 2 is part of the Ich-1 subfamily. It is one of the most conserved caspases in different species of animal. Caspase 2 has a similar amino acid sequence to initiator caspases, including caspase 1, caspase 4, caspase 5, and caspase 9. It is produced as a zymogen, which contains a long pro-domain that is similar to that of caspase 9 and contains a protein interaction domain known as a CARD domain. Pro-caspase-2 contains two subunits, p19 and |
Immunogen | Source Note: This monoclonal antibody is produced by immunizing animals with a polypeptide corresponding to Caspase-2 protein. |
Other Names | [Neural precursor cell expressed developmentally down-regulated protein 2; NEDD-2; Protease ICH-1; ICH1; NEDD2], [CASP2; CASP2; ICH1; NEDD2; CASP-2; NEDD-2; PPP1R57; ICH1; NEDD2; CASP-2; NEDD-2] |
Gene, Accession # | [CASP-2], Gene ID: 835, NCBI: NP_001215.1, UniProt: P42575 |
Catalog # | MBS435300 |
Price | $350, $565 |
Order / More Info | Caspase-2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |