UHRF1 (N-term) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | UHRF1 (N-term) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.5 |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This UHRF1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 592-626 amino acids from the N-terminal region of human UHRF1. Multidomain protein that acts as a key epigenetic regulator by bridging DNA methylation and chromatin modification. Specifically recognizes and binds hemimethylated DNA at replication forks via its YDG domain and recruits DNMT1 methyltransferase to ensure faithful propagation of the DNA methylation patterns through DNA replication. In addition to its role in maintenance of DNA methylation, also plays a key role in chromatin modification: through its tudor-like regions and PHD- type zinc fingers, specifically recognizes and binds histone H3 trimethylated at 'Lys-9' (H3K9me3) a |
| Immunogen | n/a |
| Other Names | [E3 ubiquitin-protein ligase UHRF1; 632-; Inverted CCAAT box-binding protein of 90 kDa; Nuclear protein 95; Nuclear zinc finger protein Np95; HuNp95; hNp95; RING finger protein 106; Transcription factor ICBP90; Ubiquitin-like PHD and RING finger domain-containing protein 1; hUHRF1; Ubiquitin-like-containing PHD and RING finger domains protein 1; UHRF1; ICBP90; NP95; RNF106] |
| Gene, Accession # | [UHRF1], Gene ID: 29128, NCBI: NP_001041666.1, UniProt: Q96T88 |
| Catalog # | MBS9209910 |
| Price | $165, $370 |
| Order / More Info | UHRF1 (N-term) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Hopfner R.,et al.Cancer Res. 60:121-128(2000). Muto M.,et al.Radiat. Res. 166:723-733(2006). Davenport J.W.,et al.Submitted (JUN-2000) to the EMBL/GenBank/DDBJ databases. Bechtel S.,et al.BMC Genomics 8:399-399(2007). Ota T.,et al.Nat. Genet. 36:40-45(2004). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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