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Antigenic Specificity | GRP94 / HSP90B1 (Endoplasmic Reticulum Marker) |
Clone | [SPM249] |
Host Species | Rat |
Reactive Species | human, monkey, horse, cow, sheep, porcine, rabbit, dog, rat, mouse, hamster, guinea pig, chicken, Xenopus laevis |
Isotype | IgG2a, kappa |
Format | unconjugated |
Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA at 1mg/ml) |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB), Immunohistochemistry (IHC) Formalin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes a protein of 94kDa, which is identified as the glucose-regulated protein 94 (grp94) and also tumor rejection antigen (gp96). Grp94 shows a high degree of sequence homology with the heat shock protein 90 (hsp90). This MAb is highly specific to grp94 and shows minimal cross-reaction with other members of the HSP90 family. Grp s are a class of proteins unresponsive to heat shock and are induced by glucose deprivation. Grp94 has been briefly studied as a prognostic factor in breast cancer. |
Immunogen | Immunogen: Purified glucose regulated protein 94 (grp94) from chicken oviducts |
Other Names | [Glucose Regulated Protein 94; 94kDa glucose-regulated protein, Endoplasmin, Endothelial cell (HBMEC) glycoprotein (ECGP), Heat shock protein 90kDa beta member 1 (HSP90B1), Stress inducible tumor rejection antigen GP96, TRA1, Tumor rejection antigen-1 (gp96)], [HSP90B1; HSP90B1; ECGP; GP96; TRA1; GRP94; HEL35; HEL-S-125m; GRP94; TRA1; GRP-94] |
Gene, Accession # | [HSP90B1], Gene ID: 7184, NCBI: NP_003290.1, UniProt: P14625 |
Catalog # | MBS438968 |
Price | $190, $340, $340 |
Order / More Info | GRP94 / HSP90B1 (Endoplasmic Reticulum Marker) Antibody from MYBIOSOURCE INC. |
Product Specific References | Sorger, P.K. et al. J. Mol. Biol. 194: 341-344 (1987). Tandon, A.K. et.al. Breast Cancer Res. and Treat. 16: 146 (1990). |