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Antigenic Specificity | Human CD29 |
Clone | [TS2/16.2.1] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.025 mg, 0.1 mg |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD29 is a 130 kD single chain type I glycoprotein also known as integrin beta1, VLA-beta chain, or gpIIa. It is broadly expressed on a majority of hematopoietic and non-hematopoietic cells, including leukocytes (although at low level on granulocytes), platelets, fibroblasts, endothelial cells, epithelial cells, and mast cells. CD29 is a member of the integrin family. It is non-covalently associated with integrin alpha1-alpha6 chains to form VLA-1 to VLA-6 molecules, respectively. Integrins, which include CD29, bind to several cell surface (e.g. VCAM-1, MadCAM-1) and extracellular matrix molecules. CD29 acts as a fibronectin receptor and is involved in a variety of cell-cell and cell-matrix interactions. |
Immunogen | n/a |
Other Names | [Human CD29; Integrin beta-1; ITB1; Itgb1; Fibronectin receptor subunit beta; VLA-4 subunit beta; CD29] |
Gene, Accession # | [CD29], Gene ID: 3688, NCBI: NP_002202.2, UniProt: P05556 |
Catalog # | MBS2553827 |
Price | $85, $145 |
Order / More Info | Human CD29 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Hemler M. 1990. Annu. Rev. Immunol. 8:365. 2. Hynes R. 1992. Cell 69:11. |