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Antigenic Specificity | IL-17 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Interleukin 17 (IL-17) is a family of pro-inflammatory cytokines produced by activated T cells and is thought to have a major role in the initiation and perpetuation of rheumatoid arthritis. IL-17 regulates the activities of NF-kB and mitogen-activated protein kinases such as ERK and JNK. In addition, IL-17 stimulates the expression of IL-6 and cyclooxygenase-2 and enhances the production of nitric oxide. IL-17-producing T helper cells (TH-17 cells) have been the subject of much attention due to the importance of IL-17 in the pathogenesis of autoimmune inflammation. Because of its role in autoimmune diseases, it is thought that targeting the production and action of IL-17 would be beneficial therapeutically in these diseases. |
Immunogen | Immunogen Type: Peptide Immunogen Description: Raised against a 19 amino acid peptide from near the center of human IL-17A. |
Other Names | [Interleukin-17, IL-17A, CTLA8] |
Gene, Accession # | [IL-17], Gene ID: 3605, NCBI: NP_002181 |
Catalog # | MBS9403409 |
Price | $320 |
Order / More Info | IL-17 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |