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Antigenic Specificity | Human CEACAM8 |
Clone | [GM2H6] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | Protein G purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), CELISA, ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: anti-human CEACAM8 (CD66b/NCA-95). Background: CEA-related cell adhesion molecule 8 (CEACAM8, CD66b) belongs to the carcinoembryonic antigen (CEA) gene family (1,3,4). It encodes a glycosylphosphatidylinositol (GPI)-linked glycoprotein with a Mr of 95,000 which is expressed in cells of the granulocyte-lineage. It is expressed in neutrophils and eosinophils and is characterized as a granulocyte-specific activation antigen. CEACAM8 could serve as a marker for granulocyte activities (2). Like all members of the CEA family, it consists of a single N domain, with structural homology to the immunoglobulin variable domains, followed by two immunoglobulin constant-like A and B domains. |
Immunogen | Immunogen: Immunogen: cDNA |
Other Names | [CD66b; NCA-95], [CEACAM8; CEACAM8; CD67; CGM6; CD66b; NCA-95; CGM6] |
Gene, Accession # | Gene ID: 1088, NCBI: NP_001807.2, UniProt: P31997 |
Catalog # | MBS468020 |
Price | $505 |
Order / More Info | Human CEACAM8 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Zimmermann W (2002). Carcinoembryonic antigen. In Wiley Encyclopedia of Molecular Medicine (T. Creighton,ed.), John Wiley & Sons Inc., New York, USA, pp. 459-462.2. Zhao L, Xu S, Fjaertoft G, Pauksen K, Hakansson L and Venge P (2004). An enzyme-linked immunosorbentassay for human carcinoembryonic antigen-related cell adhesion molecule 8, a biological marker of granulocyteactivities in vivo. J. Immunol. Methods 293(1-2):207-14Hammarstrom S (1999). The carcinoembryonic antigen (CEA) family: structures, suggested functions andexpression in normal and malignant tissues. Semin. Cancer Biol. 9, 67-81. |