Human CEACAM8 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman CEACAM8
Clone[GM2H6]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1
FormatProtein G purified
Size0.1 mg
Concentrationn/a
ApplicationsFlow Cytometry (FC/FACS), CELISA, ELISA (EIA)
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DescriptionSpecificity: anti-human CEACAM8 (CD66b/NCA-95). Background: CEA-related cell adhesion molecule 8 (CEACAM8, CD66b) belongs to the carcinoembryonic antigen (CEA) gene family (1,3,4). It encodes a glycosylphosphatidylinositol (GPI)-linked glycoprotein with a Mr of 95,000 which is expressed in cells of the granulocyte-lineage. It is expressed in neutrophils and eosinophils and is characterized as a granulocyte-specific activation antigen. CEACAM8 could serve as a marker for granulocyte activities (2). Like all members of the CEA family, it consists of a single N domain, with structural homology to the immunoglobulin variable domains, followed by two immunoglobulin constant-like A and B domains.
ImmunogenImmunogen: Immunogen: cDNA
Other Names[CD66b; NCA-95], [CEACAM8; CEACAM8; CD67; CGM6; CD66b; NCA-95; CGM6]
Gene, Accession #Gene ID: 1088, NCBI: NP_001807.2, UniProt: P31997
Catalog #MBS468020
Price$505
Order / More InfoHuman CEACAM8 Antibody from MYBIOSOURCE INC.
Product Specific References1. Zimmermann W (2002). Carcinoembryonic antigen. In Wiley Encyclopedia of Molecular Medicine (T. Creighton,ed.), John Wiley & Sons Inc., New York, USA, pp. 459-462.2. Zhao L, Xu S, Fjaertoft G, Pauksen K, Hakansson L and Venge P (2004). An enzyme-linked immunosorbentassay for human carcinoembryonic antigen-related cell adhesion molecule 8, a biological marker of granulocyteactivities in vivo. J. Immunol. Methods 293(1-2):207-14Hammarstrom S (1999). The carcinoembryonic antigen (CEA) family: structures, suggested functions andexpression in normal and malignant tissues. Semin. Cancer Biol. 9, 67-81.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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