Lipocalin 2 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Lipocalin 2 |
| Clone | polyclonal |
| Host Species | n/a |
| Reactive Species | mouse, rat |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Description: Rabbit IgG polyclonal antibody for Neutrophil gelatinase-associated lipocalin(LCN2) detection. Tested with WB, IHC-P, ELISA in Mouse; Rat. Background: Europhile gelatinase-associated lipocalin (NGAL) is a protein that in humans is encoded by the LCN2 gene. The binding of lipocalin-2 to bacterial siderophores is important in the innate immune response to bacterial infection. Upon encountering invading bacteria the toll-like receptors on immune cells stimulate the synthesis and secretion of lipocalin-2. Secreted lipocalin-2 then limits bacterial growth by sequestering iron-containing siderophores. Lipocalin-2 also functions as a growth factor. |
| Immunogen | Immunogen: E Coli-derived rat Lipocalin 2 recombinant protein (Position: Q21-N198). Rat Lipocalin 2 shares 64.4 % and 81.1 % amino acid (aa) sequence identity with human and mouse Lipocalin 2, respectively. Ig Type: Rabbit IgG |
| Other Names | [Neutrophil gelatinase-associated lipocalin; 24p3; 25 kDa alpha 2 microglobulin related subunit of MMP9; 25 kDa alpha-2-microglobulin-related subunit of MMP-9; Alpha 2 microglobulin related protein; HGNC:6526; HNL; Lcn 2; Lcn2; Lipocalin-2; Migration stimulating factor inhibitor; MSFI; Neutrophil gelatinase associated lipocalin; Neutrophil gelatinase associated lipocalin precursor; Neutrophil gelatinase-associated lipocalin; NGAL; NGAL_HUMAN; Oncogene 24p3; Oncogenic lipocalin 24p3; P25; Siderocalin; siderocalin LCN2; SV40 induced 24P3 protein; Uterocalin; lipocalin 2], [Lcn2; Lcn2; Sip24; NGAL] |
| Gene, Accession # | Gene ID: 170496, NCBI: NP_570097.1, UniProt: P30152 |
| Catalog # | MBS178180 |
| Price | $315 |
| Order / More Info | Lipocalin 2 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Cowland JB, Borregaard N (October 1997). Molecular characterization and pattern of tissue expression of the gene for neutrophil gelatinase-associated lipocalin from humans. Genomics 45 (1): 17-23. 2. Chan P, Simon-Chazottes D, Mattei MG, Guenet JL, Salier JP (September 1994). Comparative mapping of lipocalin genes in human and mouse: the four genes for complement C8 gamma chain, prostaglandin-D-synthase, oncogene-24p3, and progestagen-associated endometrial protein map to HSA9 and MMU2. Genomics 23 (1): 145-50. 3. Flo TH, Smith KD, Sato S, Rodriguez DJ, Holmes MA, Strong RK, Akira S, Aderem A (December 2004). Lipocalin 2 mediates an innate immune response to bacterial infection by sequestrating iron. Nature 432 (7019): 917-21. 4. Kjeldsen L, Johnsen AH, Sengelov H, Borregaard N (May 1993). Isolation and primary structure of NGAL, a novel protein associated with human neutrophil gelatinase. J. Biol. Chem. 268 (14): 10425-32. 5. Nelson AM, Zhao W, Gilliland KL, Zaenglein AL, Liu W, Thiboutot DM (April 2008). 6. Schmidt-Ott KM, Mori K, Li JY, Kalandadze A, Cohen DJ, Devarajan P, Barasch J (February 2007). Dual action of neutrophil gelatinase-associated lipocalin. J. Am. Soc. Nephrol. 18 (2): 407-13. |
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MYBIOSOURCE INC.
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