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Antigenic Specificity | HDAC1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP), CHIP |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Acetylation of the histone tail causes chromatin to adopt an open conformation, allowing increased accessibility of transcription factors to DNA. The identification of histone acetyltransferases (HATs) and their large multiprotein complexes has yielded important insights into how these enzymes regulate transcription (1,2). HAT complexes interact with sequence-specific activator proteins to target specific genes. In addition to histones, HATs can acetylate nonhistone proteins, suggesting multiple roles for these enzymes (3). In contrast, histone deacetylation promotes a closed chromatin conformation and typically leads to repression of gene activity (4). Mammalian histone deacetylases can be divided into three classes on the basis of the |
Immunogen | Immunogen: N term -peptide of human HDAC1 Calculated Molecular Weight: 55kDa |
Other Names | [HDAC1; DKFZp686H12203; GON-10; HD1; RPD3; RPD3L1], [HDAC1; HDAC1; HD1; RPD3; GON-10; RPD3L1; RPD3L1; HD1] |
Gene, Accession # | [HDAC1], Gene ID: 3065, NCBI: Q13547.1, UniProt: Q13547 |
Catalog # | MBS125289 |
Price | $200, $275, $430 |
Order / More Info | HDAC1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |