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Antigenic Specificity | Human CD294 (N-TERMINAL) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse (expected from sequence), rat (expected from sequence) |
Isotype | n/a |
Format | unconjugated |
Size | 0.05 mg |
Concentration | IgG concentration 1.0mg/ml |
Applications | ELISA (EIA), Immunohistology Paraffin, Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This item recognises CD294, also known as chemoattractant receptor homologous molecule expressed on Th2 cells (CRTH2) and GRP44. . . CD294 is a G protein-coupled receptor which has a high affinity for prostaglandin D2 (PGD2). . . CD294 is predominantly expressed on Th2 cells, basophils and eosinophils, and its activation by PDG2 mediates chemotaxis of these cells to inflammatory sites. CD294 may be a useful marker for Th2 cells, and enhances their function and signalling with a possible role in Th2 cell differentiation. . . PGD2 is thought to contribute to bronchoconstriction, eosinophilia and mucus production in allergic asthma, and CD294 may contribute to this disease. MBS224236 recognises CD294, also known as chemoattractant recept |
Immunogen | Immunogen: A synthetic peptide corresponding to an 18 amino acid sequence from near the amino terminus of human CD294 - KLH conjugated. Histology Positive Control Tissue: Human adrenal gland Buffer Solution: Phosphate buffered saline Antiserum Preparation: Antisera to human CD294 were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG prepared from whole serum by affinity chromatography. Target Species: Human |
Other Names | [prostaglandin D2 receptor 2; Prostaglandin D2 receptor 2; prostaglandin D2 receptor 2; G protein-coupled receptor 44; G-protein coupled receptor 44; PGD2 receptor; chemoattractant receptor-homologous molecule expressed on TH2 cells; prostaglandin D2 receptor CRTH2; prostaglandin D2 receptor 2; Chemoattractant receptor-homologous molecule expressed on Th2 cells; G-protein coupled receptor 44; CD_antigen: CD294, Gpr44], [Ptgdr2; Ptgdr2; Crth2; Gpr44; Grp45; Crth2] |
Gene, Accession # | [CD294], Gene ID: 14764, NCBI: NP_034092.1 |
Catalog # | MBS224236 |
Price | $550 |
Order / More Info | Human CD294 (N-TERMINAL) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |