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Antigenic Specificity | SNAI2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Protein G purified |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Transcriptional repressor that modulates both activator-dependent and basal transcription. Involved in the generation and migration of neural crest cells. Plays a role in mediating RAF1-induced transcriptional repression of the TJ protein, occludin (OCLN) and subsequent oncogenic transformation of epithelial cells (By similarity). Represses BRCA2 expression by binding to its E2-box-containing silencer and recruiting CTBP1 and HDAC1 in breast cells. In epidermal keratinocytes, binds to the E-box in ITGA3 promoter and represses its transcription. Involved in the regulation of ITGB1 and ITGB4 expression and cell adhesion and proliferation in epidermal keratinocytes. Binds to E-box2 domain of BSG and activates its expression during TGFB1-induce |
Immunogen | Immunogen: Recombinant human Zinc finger protein SNAI2 protein (12-124AA) |
Other Names | [Zinc finger protein SNAI2; Neural crest transcription factor Slug; Protein snail homolog 2; SNAI2; SLUG; SLUGH] |
Gene, Accession # | [SNAI2], Gene ID: 6591, NCBI: NP_003059.1, UniProt: O43623 |
Catalog # | MBS7049184 |
Price | $160, $235 |
Order / More Info | SNAI2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |