DcR2 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityDcR2
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mg
Concentrationn/a
ApplicationsELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC)
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DescriptionDcR2 Antibody: Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors. TRAIL/Apo2L is a new member of the TNF family and induces apoptosis of a variety of tumor cell lines. DR4 and DR5 are the recently identified functional receptors for TRAIL, and DcR1/TRID is a decoy receptor. Another member of the TRAIL receptor family was more recently identified and designated DcR2, TRAIL-R4, or TRUNDD. DcR2 has an extracellular TRAIL-binding domain but lacks intracellular death domain and does not induce apoptosis. Like DR4 and DR5, DcR2 transcript is widely expressed in normal human tissues. Overexpression of DcR2 attenuated TRAIL-induced apoptosis.
ImmunogenImmunogen: DcR2 antibody was raised against a 15 amino acid peptide near the center of human DcR2. Buffer: DcR2 Antibody is supplied in PBS containing 0.02% sodium azide.
Other Names[DcR2; DCR2; CD264; TRUNDD; TRAILR4; TRAIL-R4; DCR2; UNQ251/PRO288; Tumor necrosis factor receptor superfamily member 10D; Decoy receptor 2; DcR2; tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain], [TNFRSF10D; TNFRSF10D; DCR2; CD264; TRUNDD; TRAILR4; TRAIL-R4; DCR2; TRAILR4; TRUNDD; DcR2; TRAIL receptor 4; TRAIL-R4]
Gene, Accession #[TNFRSF10D], Gene ID: 8793, NCBI: Q9UBN6.1, UniProt: Q9UBN6
Catalog #MBS151536
Price$375
Order / More InfoDcR2 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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