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Antigenic Specificity | DcR2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | DcR2 Antibody: Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors. TRAIL/Apo2L is a new member of the TNF family and induces apoptosis of a variety of tumor cell lines. DR4 and DR5 are the recently identified functional receptors for TRAIL, and DcR1/TRID is a decoy receptor. Another member of the TRAIL receptor family was more recently identified and designated DcR2, TRAIL-R4, or TRUNDD. DcR2 has an extracellular TRAIL-binding domain but lacks intracellular death domain and does not induce apoptosis. Like DR4 and DR5, DcR2 transcript is widely expressed in normal human tissues. Overexpression of DcR2 attenuated TRAIL-induced apoptosis. |
Immunogen | Immunogen: DcR2 antibody was raised against a 15 amino acid peptide near the center of human DcR2. Buffer: DcR2 Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [DcR2; DCR2; CD264; TRUNDD; TRAILR4; TRAIL-R4; DCR2; UNQ251/PRO288; Tumor necrosis factor receptor superfamily member 10D; Decoy receptor 2; DcR2; tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain], [TNFRSF10D; TNFRSF10D; DCR2; CD264; TRUNDD; TRAILR4; TRAIL-R4; DCR2; TRAILR4; TRUNDD; DcR2; TRAIL receptor 4; TRAIL-R4] |
Gene, Accession # | [TNFRSF10D], Gene ID: 8793, NCBI: Q9UBN6.1, UniProt: Q9UBN6 |
Catalog # | MBS151536 |
Price | $375 |
Order / More Info | DcR2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |