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Antigenic Specificity | Proprotein convertase subtilisin/kexin type 9 (PCSK9), NARC1 BLOCKING EPITOPE |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 0.1 mg |
Concentration | 0.35mg/ml |
Applications | Western Blot (WB), Functional epitope reported to block PCSK9-LDLR interaction, ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This anitbody is made to an epitope that is reported to block the PCSK9?LDLR (low density lipoprotein receptor) interaction. PCSK9 binds to the EGF-A domain of the LDLR and signals LDLR degradation. Reduced LDLR levels result in decreased LDL (low density lipid) metabolism leading to hypercholesterolemia. |
Immunogen | Immunogen: Synthetic peptide derived from the human PCSK9 protein reported to block PCSK9-LDLR interaction. |
Other Names | [Proprotein convertase PC9; Subtilisin/kexin-like protease PC9; Neural apoptosis-regulated convertase 1], [PCSK9; PCSK9; FH3; PC9; NARC1; LDLCQ1; NARC-1; HCHOLA3; NARC1; NARC-1; PC9] |
Gene, Accession # | [PCSK9], Gene ID: 255738, NCBI: NP_777596.2, UniProt: Q8NBP7 |
Catalog # | MBS395898 |
Price | $340 |
Order / More Info | Proprotein convertase subtilisin/kexin type 9 (PCSK9), NARC1 BLOCKING EPITOPE Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |