Edit |   |
---|---|
Antigenic Specificity | AR alpha2C |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, Immunofluorescence (IF), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: AR alpha2C Polyclonal Antibody detects endogenous levels of AR alpha2C protein. Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. The mouse studies revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons. The alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated |
Immunogen | Immunogen: Synthesized peptide derived from the C-terminal region of human AR alpha2C at AA range: 310-390 |
Other Names | [Rabbit AR alpha2C; ADRA2L2; ADRA2RL2; Alpha-2C adrenergic receptor; Alpha-2 adrenergic receptor subtype C4; Alpha-2C adrenoreceptor; Alpha-2C adrenoceptor; Alpha-2CAR] |
Gene, Accession # | [ADRA2C], Gene ID: 152, NCBI: NP_000674.2, UniProt: P18825 |
Catalog # | MBS9701424 |
Price | $130, $220, $325 |
Order / More Info | AR alpha2C Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |