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Antigenic Specificity | Jun B |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, Immunoprecipitation (IP), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Jun B Polyclonal Antibody detects endogenous levels of Jun B protein. JunB is a basic region, leucine zipper (bZIP) transcription factor belonging to the Jun family that includes c-Jun and JunD. Jun family members homodimerize or heterodimerize with Fos and ATF proteins to form a functional transcription factor AP-1 (activator protein 1), whose activity is regulated by a variety of physiological and pathological stimuli such as growth factors, infections, and stress signals. While JunB sometimes antagonizes c-Jun transcriptional activity, it may functionally substitute for c-Jun during development in mice. JunB regulates hematopoietic stem cell number and plays an important role in the pathogenesis of chronic myelogenous leukem |
Immunogen | Immunogen: Synthesized peptide derived from human Jun B around the non-phosphorylation site of S259 |
Other Names | [Rabbit Jun B; Transcription factor jun-B] |
Gene, Accession # | [JUNB], Gene ID: 3726, NCBI: NP_002220.1, UniProt: P17275 |
Catalog # | MBS9705621 |
Price | $130, $220, $325 |
Order / More Info | Jun B Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |