Human XAF1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman XAF1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatimmunoaffinity purified
Size0.05 mg
Concentration1 mg/ml
ApplicationsImmunohistochemistry (IHC - Paraffin), Western Blot (WB)
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DescriptionSpecificity: synthetic peptide corresponding to 16 amino acids near the middle of human XAF-1. XAF-1 binds to XIAP, an inhibitor of caspases-3, -7, and -9, and triggers its relocation from the cytosol to the nucleus. Overexpression of XAF-1 results in the neutralization of XIAP's ability to inhibit cell death. XAF-1 is normally expressed in all adult and fetal tissues but was found to be present in very low levels in a variety of cancer cell lines. In contrast, XIAP levels have been shown to be high in a majority of cell lines.
ImmunogenImmunogen Description: Synthetic peptide from human XAF1.
Other Names[XAF1 IHC-plus; XAF1; BIRC4 binding protein; BIRC4-binding protein; BIRC4BP; HSXIAPAF1; XIAP-associated factor 1; XIAPAF1; XIAP associated factor 1; Human XAF1], [XAF1; XAF1; BIRC4BP; XIAPAF1; HSXIAPAF1; BIRC4BP; XIAPAF1]
Gene, Accession #[XAF1], Gene ID: 54739, NCBI: NP_059993.2, UniProt: Q6GPH4
Catalog #MBS241350
Price$660
Order / More InfoHuman XAF1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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