Germinal Center Kinase (GCK/MAP4K2) (Center), 288-319 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Germinal Center Kinase (GCK/MAP4K2) (Center), 288-319 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 1.42 |
| Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This Germinal Center Kinase (GCK/MAP4K2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 288-319 amino acids from the Central region of human Germinal Center Kinase (GCK/MAP4K2). The protein encoded by this gene is a member of the serine/threonine protein kinase family. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B-cell differentiation. This kinase can be activated by TNF-alpha, and has been shown to specifically activate MAP kinases. This kinase is also found to interact with TNF receptor-associated factor 2 (TRAF2), which is involved in the activation of MAP3K1/MEKK1. |
| Immunogen | n/a |
| Other Names | [Mitogen-activated protein kinase kinase kinase kinase 2; B lymphocyte serine/threonine-protein kinase; Germinal center kinase; GC kinase; MAPK/ERK kinase kinase kinase 2; MEK kinase kinase 2; MEKKK 2; Rab8-interacting protein; MAP4K2; GCK; RAB8IP] |
| Gene, Accession # | [MAP4K2], Gene ID: 5871, NCBI: NP_004570.2, UniProt: Q12851 |
| Catalog # | MBS9208481 |
| Price | $165, $370 |
| Order / More Info | Germinal Center Kinase (GCK/MAP4K2) (Center), 288-319 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Chadee, D.N., et al., Mol. Cell. Biol. 22(3):737-749 (2002). Katz, P., et al., J. Biol. Chem. 269(24):16802-16809 (1994). |
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MYBIOSOURCE INC.
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