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Antigenic Specificity | SIN3A - middle region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Acts as a transcriptional repressor. Corepressor for REST. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Also interacts with MXD1-MAX heterodimers to repress transcription by tethering SIN3A to DNA. Acts cooperatively with OGT to repress transcription in parallel with histone deacetylation. Involved in the control of the circadian rhythms. Required for the transcriptional repression of circadian target genes, such as PER1, mediated by the large PER complex through histone deacetylation. Cooperates with FOXK1 to regulate cell cycle progression probably by repressing cell cycle inhibitor genes expression. |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the middle region of mouse SIN3A |
Other Names | [paired amphipathic helix protein Sin3a isoform 2; Paired amphipathic helix protein Sin3a; paired amphipathic helix protein Sin3a; transcriptional regulator, SIN3A (yeast); Histone deacetylase complex subunit Sin3a; Transcriptional corepressor Sin3a] |
Gene, Accession # | [SIN3A], Gene ID: 20466, NCBI: NP_001103820.1, UniProt: Q60520 |
Catalog # | MBS3223621 |
Price | $335 |
Order / More Info | SIN3A - middle region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |