Edit |   |
Antigenic Specificity | Mouse Mapk14 (N-term), 26-53 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted reactivity: rat) |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This Mouse Mapk14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 26-53 amino acids from the N-terminal region of mouse Mapk14. Responds to activation by environmental stress, pro-inflammatory cytokines and lipopolysaccharide (LPS) by phosphorylating a number of transcription factors, such as ELK1 and ATF2 and several downstream kinases, such as MAPKAPK2 and MAPKAPK5. Plays a critical role in the production of some cytokines, for example IL-6. Required in mid-fetal development for the growth of embryo-derived blood vessels in the labyrinth layer of the placenta. Also plays an essential role in developmental and stress-induced erythropoiesis, through regulation of EPO gene expression. |
Immunogen | n/a |
Other Names | [Mitogen-activated protein kinase 14; MAP kinase 14; MAPK 14; CRK1; Mitogen-activated protein kinase p38 alpha; MAP kinase p38 alpha; Mapk14; Crk1; Csbp1; Csbp2] |
Gene, Accession # | [Mapk14], Gene ID: 26416, NCBI: NP_001161980.1, UniProt: P47811 |
Catalog # | MBS9207550 |
Price | $165, $370 |
Order / More Info | Mouse Mapk14 (N-term), 26-53 Antibody from MYBIOSOURCE INC. |
Product Specific References | Pan, W.W., et al. J. Biol. Chem. 285(45):34348-34354(2010) Menon, M.B., et al. J. Biol. Chem. 285(43):33242-33251(2010) Chandrakesan, P., et al. J. Biol. Chem. 285(43):33485-33498(2010) Ferreiro, I., et al. J. Biol. Chem. 285(41):31819-31828(2010) Smeeton, J., et al. Development 137(19):3233-3243(2010) |