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Antigenic Specificity | HER2 (Phospho-Tyr877) |
Clone | polyclonal |
Host Species | n/a |
Reactive Species | n/a |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mL |
Concentration | n/a |
Applications | Immunoblotting (IB), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody detects endogenous human, mouse, and rat HER2 only when phosphorylated at tyrosine 877. HER2 is a member of the human epidermal growth factor receptor (HER/EGFR/ERBB) family. Amplification or over-expression of this oncogene has been shown to play an important role in the development and progression of certain aggressive types of breast cancer. In recent years HER2 has become an important biomarker and target of therapy for approximately 30% of breast cancer patients. |
Immunogen | Antigen: Peptide sequence that includes phosphorylation site of tyrosine 877 (T-E-Y(p)-H-A) derived from human HER2 and conjugated to KLH. |
Other Names | [receptor tyrosine-protein kinase erbB-2 isoform b; Receptor tyrosine-protein kinase erbB-2; receptor tyrosine-protein kinase erbB-2; erb-b2 receptor tyrosine kinase 2; Metastatic lymph node gene 19 protein; MLN 19; Proto-oncogene Neu; Proto-oncogene c-ErbB-2; Tyrosine kinase-type cell surface receptor HER2; p185erbB2; CD_antigen: CD340], [ERBB2; ERBB2; NEU; NGL; HER2; TKR1; CD340; HER-2; MLN 19; HER-2/neu; HER2; MLN19; NEU; NGL; MLN 19] |
Gene, Accession # | [HER2], Gene ID: 2064, NCBI: NP_001005862.1, UniProt: P04626 |
Catalog # | MBS191086 |
Price | $340 |
Order / More Info | HER2 (Phospho-Tyr877) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |