Survivin Antibody from MYBIOSOURCE INC.

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Antigenic SpecificitySurvivin
Clone[32,1]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1
FormatProtein G purified
Size0.1 mg
Concentrationn/a
ApplicationsFlow Cytometry (FC/FACS), Western Blot (WB)
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DescriptionRecognizes human Survivin. Survivin is a 16.5 kDa protein and the smallest inhibitor of apoptosis (IAP) so far identified. It is involved in the inhibition of apoptosis and cell division. Survivin expression has been reported at high levels in embryonic tissues, but at low or non-detectable levels in normal tissue. Survivin regulates the G2/M phase of the cell cycle by associating with the mitotic spindle microtubules and directly inhibits Caspase-3 and Caspase-7. Survivin is selectively expressed in the most common human cancers and is associated with clinical tumor progression. It has been proposed as a tumor marker for breast cancer, and Survivin expression has been correlated to clinical outcome in melanoma patients. Down-regulation or
ImmunogenImmunogen: Synthetic peptide corresponding to aa 3-19 of the nuclear form of survivin.
Other Names[Baculoviral IAP repeat-containing protein 5; Baculoviral IAP repeat-containing protein 5; baculoviral IAP repeat-containing protein 5; baculoviral IAP repeat containing 5; Apoptosis inhibitor 4; Apoptosis inhibitor survivin], [BIRC5; BIRC5; API4; EPR-1; API4; IAP4]
Gene, Accession #[BIRC5; EPR1], Gene ID: 332, NCBI: O15392.3, UniProt: O15392
Catalog #MBS565086
Price$385
Order / More InfoSurvivin Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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