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Antigenic Specificity | Survivin |
Clone | [32,1] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | Protein G purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes human Survivin. Survivin is a 16.5 kDa protein and the smallest inhibitor of apoptosis (IAP) so far identified. It is involved in the inhibition of apoptosis and cell division. Survivin expression has been reported at high levels in embryonic tissues, but at low or non-detectable levels in normal tissue. Survivin regulates the G2/M phase of the cell cycle by associating with the mitotic spindle microtubules and directly inhibits Caspase-3 and Caspase-7. Survivin is selectively expressed in the most common human cancers and is associated with clinical tumor progression. It has been proposed as a tumor marker for breast cancer, and Survivin expression has been correlated to clinical outcome in melanoma patients. Down-regulation or |
Immunogen | Immunogen: Synthetic peptide corresponding to aa 3-19 of the nuclear form of survivin. |
Other Names | [Baculoviral IAP repeat-containing protein 5; Baculoviral IAP repeat-containing protein 5; baculoviral IAP repeat-containing protein 5; baculoviral IAP repeat containing 5; Apoptosis inhibitor 4; Apoptosis inhibitor survivin], [BIRC5; BIRC5; API4; EPR-1; API4; IAP4] |
Gene, Accession # | [BIRC5; EPR1], Gene ID: 332, NCBI: O15392.3, UniProt: O15392 |
Catalog # | MBS565086 |
Price | $385 |
Order / More Info | Survivin Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |